PKPD102 Clinical Pharmacology Basics

Clinical Pharmacology is the study of the interactions between the human body and drugs. This module will help you understand the basic principles of Clinical Pharmacology and the range of “Phase 1” studies used to uncover these interactions.

Vocabulary

Absorption, Auricular administration, Bioavailability, Blood/brain barrier, Buccal administration, Capillary, Concentration, Distribution, Dose, Dose Response, Drug disposition, Duration of action, Excretion/ Elimination, First pass effect, First pass metabolism, Genetic polymorphisms, half maximal effective concentration (Ec50), Heavy first pass effect, Hepatic portal vein, Hyperbolic curve, Informed decision, Inhaled administration, intraarterial administration, Intramuscular administration, Intranasal administration, Intrathecal administration, Intravaginal administration, Intravenous administration, Liver, Logarithm, Lumen, Maximum tolerated concentration (MTC), Mechanism of action (MOA), Metabolism, Minimum effective concentration (MEC), Multiple ascending dose study (MAD), Nitrates, Ocular administration, Oral administration, Pharmacodynamics (PD), Pharmacokinetics (PK), Plasma concentration, Plasma concentration, Potency, Rectal administration, Routes of administration, Selectivity, Sigmoid curve, Site of action, Subcutaneous administration, Sublingual administration, Subtherapeutic, Systemic circulation, Therapeutic effect, Therapeutic index (TI), Therapeutic range, Threshold dose, Toxic effect, Transdermal administration